The study aimed to develop pre-clinical diagnosis of Alzheimer's disease (AD) and - in future - preventive therapy in patients with mild cognitive impairment (MCI). The MCI group (n=44) and AD group (n=42, including 18 patients with soft dementia and 24 patients with mild dementia) were studied. The groups were matched for age (median 70 and 69 years for MCI and AD groups, respectively). The control group comprised 24 mentally healthy relatives of the patients.

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[Platelet cytochrome c-oxidase and glutamine synthetase-like protein in patients with mild cognitive impairment]. [Article in Russian]. Burbaeva GSh, Boksha IS,. IrriCAD Pro is an advanced computer-aided design (CAD) software for designing and optimizing pressurized irrigation systems. Far more than just a drawing.

Correlations between the activity/amounts of platelet enzymes: cytochrome c-oxidase (COX), glutamine synthetase-like protein (GSLP) and the extent of cognitive impairment were studied. The COX activity in MCI and AD groups was significantly lower than in the control group (Kruskal-Wallis test p=0.0001, χ²=11.6, p=0.003). These tests showed significant differences in GSLP amount between three groups (p=0.04 and χ²=9.38, p=0.01, respectively). Significant reverse correlation (Spearman R= -0.43, p=0.007) was found between GSLP amount and MMSE scores for MCI+AD group, i.e., the lower MMSE scores, the higher platelet GSLP level. Platelet COX and GSLP may be considered as early markers of cognitive impairment.

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IRRICAD IRRICAD™ — Available as a standalone program and now as a plug-in for AutoCAD® and BricsCAD. Go to for details about the new plug in. Benefits include fully customizable menus, improved graphical performance, familiar interface and streamlined design.

IRRICAD is a graphically based, computer-aided design package developed specifically for designing pressurized irrigation or water supply systems. IRRICAD is far more than a drawing package because it combines the advantages of CAD drawing with powerful hydraulic pipe sizing and network analysis techniques, and it also provides automatic selection of pipe fittings, thereby generating a complete bill of materials.

Vizitnaya kartochka na konkurs super mama. Systems can be designed to cover a full range of functions including: • Sprinkler/Micro sprinkler • Drip and Drip Tape • Nursery • Dust Suppression • Mainline Networks • Stock Water Systems • Residential and Commercial Turf • Sports Fields/Golf Courses • Systems Pressurized by Gravity.

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